Article
G protein-coupled receptor kinase 5 gene polymorphisms are associated with postoperative atrial fibrillation after coronary artery bypass grafting in patients receiving β-blockers.
Circulation. Cardiovascular genetics - 1 Oct 2014
Kertai Miklos D, Li Yen-Wei, Li Yi-Ju, Shah Svati H, Kraus William E, Fontes Manuel L, Stafford-Smith Mark, Newman Mark F, Podgoreanu Mihai V, Mathew Joseph P
Abstract excerpt
BACKGROUND: We hypothesized that genetic variations in the adrenergic signaling pathway and cytochrome P450 2D6 enzyme are associated with new-onset atrial fibrillation (AF) in patients who underwent coronary artery bypass grafting and were treated with perioperative β-blockers (BBs). METHODS AND RESULTS: Two cohorts of patients who underwent coronary artery bypass grafting and received perioperative BBs at Duke...
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