Article
Oncology and Pharmacogenomics Insights in Polycystic Ovary Syndrome: An Integrative Analysis.
Frontiers in endocrinology - 1 Jan 2020
Yumiceba Verónica, López-Cortés Andrés, Pérez-Villa Andy, Yumiseba Iván, Guerrero Santiago, García-Cárdenas Jennyfer M, Armendáriz-Castillo Isaac, Guevara-Ramírez Patricia, Leone Paola E, Zambrano Ana Karina, Paz-Y-Miño César
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. Epidemiological findings revealed that women with PCOS are prone to develop certain cancer types due to their shared metabolic and endocrine abnormalities. However, the mechanism that relates PCOS and oncogenesis has not been addressed. Herein, in this review...
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