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Article

Uterine Injury Caused by Genotype 4 Hepatitis E Virus Infection Based on a BALB/c Mice Model.

Viruses - 28 Sept 2021

Yang Weimin, Chen Shuangfeng, Mickael Houfack K, Xu Liangheng, Xia Yueping, Cong Chao, Zhang Yike, Qian Zhongyao, Li Tengyuan, Wei Daqiao, Yu Wenhai, Huang Fen

Abstract excerpt

To evaluate whether uterine injury caused by hepatitis E virus (HEV) infection is responsible for adverse pregnancy outcomes. HEV-infected female BALB/c mice were coupled with healthy male BALB/c mice at 0, 7, 14, 21, and 91 dpi to explore the uterine injury caused by HEV infection. Mice were euthanized after 10 days of copulation, and uteruses were collected for HEV RNA and antigen detection and...

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Identifiers

PMID: 34696377
DOI: 10.3390/v13101950
PMCID: PMC8538062

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