Article
Advances in Hepatitis E Virus Biology and Pathogenesis.
Viruses - 9 Feb 2021
Lin Shaoli, Zhang Yan-Jin
Abstract excerpt
Hepatitis E virus (HEV) is one of the causative agents for liver inflammation across the world. HEV is a positive-sense single-stranded RNA virus. Human HEV strains mainly belong to four major genotypes in the genus Orthohepevirus A, family Hepeviridae. Among the four genotypes, genotype 1 and 2 are obligate human pathogens, and genotype 3 and 4 cause zoonotic infections. HEV infection with genotype 1 and 2...
Topics
- Female
- Genome, Viral
- Genotype
- Hepatitis E
- Hepatitis E virus
- Host-Pathogen Interactions
- Humans
- Immune Evasion
- Liver
- Open Reading Frames
- Pregnancy
- Pregnancy Complications, Infectious
- RNA, Viral
- Virus Replication
