Article
Acute stress and alcohol exposure during adolescence result in an anxious phenotype in adulthood: Role of altered glutamate/endocannabinoid transmission mechanisms.
Progress in neuro-psychopharmacology & biological psychiatry - 8 Mar 2022
Sánchez-Marín Laura, Flores-López Maria, Pastor Antoni, Gavito Ana Luisa, Suárez Juan, de la Torre Rafael, Pavón Francisco Javier, Rodríguez de Fonseca Fernando, Serrano Antonia
Abstract excerpt
BACKGROUND: Stressful episodes and high alcohol consumption during adolescence are considered major risk factors for the development of psychiatric disorders in adulthood. Identification of mechanisms underlying these early events, which enhanced vulnerability to mental illness, is essential for both their prevention and treatment. METHODS: Male Wistar rats were used to investigate the long-term effects of early...
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