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Article

The Role of the Endocannabinoid System and Genetic Variation in Adolescent Brain Development.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2018

Meyer Heidi C, Lee Francis S, Gee Dylan G

Abstract excerpt

During adolescence, both rodent and human studies have revealed dynamic changes in the developmental trajectories of corticolimbic structures, which are known to contribute to the regulation of fear and anxiety-related behaviors. The endocannabinoid (eCB) system critically regulates stress responsivity and anxiety throughout the life span. Emerging evidence suggests that during adolescence, changes in eCB...

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Identifiers

PMID: 28685756
DOI: 10.1038/npp.2017.143
PMCID: PMC5719094

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