Article
Exploring Appropriate Reference Intervals and Clinical Decision Limits for Glucose-6-Phosphate Dehydrogenase Activity in Individuals From Guangzhou, China.
Annals of laboratory medicine - 1 Nov 2024
Huang Zhenyi, Li Ziyan, Li Yating, Cao Yunshan, Zhong Suping, Liu Jinlu, Lin Zhiqian, Lin Lijuan, Fang Yanping, Zeng Jing, Su Zhaoying, Li Huibin, Liang Jianfen, Zhu Biqing, Lin Zipei, Huang Yongxin, Yang Xuexi, Jiang Lingxiao
Abstract excerpt
Background: Quantitative detection of glucose-6-phosphate dehydrogenase (G6PD) is commonly done to screen for G6PD deficiency. However, current reference intervals (RIs) of G6PD are unsuitable for evaluating G6PD-activity levels with local populations or associating G6PD variants with hemolysis risk to aid clinical decision-making. We explored appropriate RIs and clinical decision limits (CDLs) for G6PD activity...
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