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Investigation of the relationship between MMP-1 (- 1607 1G/2G), MMP-3 (- 1171 5A/6A) gene variations and development of bladder cancer.

Molecular biology reports - 1 Dec 2021

Ay Arzu, Alkanli Nevra, Cevik Gokhan

Abstract excerpt

BACKGROUND: Chronic inflammation is an important risk factor in the development of bladder cancer. It may stimulate growth and metastasis of cancer cells. The inflammatory process includes MMP activities and expression. MMP activation can be stimulated by various inflammatory cells. Pathological processes such as bladder cancer may occur due to imbalance in MMP activities. In our study, we aimed to determine the...

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PMID: 34693500
DOI: 10.1007/s11033-021-06775-2

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