Article

Concurrent EGFR L858R and K860I mutations: PCR-negative but NGS-positive alterations that respond to EGFR inhibitors in non-small cell lung cancer

2024-10-23

Abstract excerpt

<title>Abstract</title> <p><bold>Introduction: </bold>Clinical routine amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) and next generation sequencing (NGS) are able to identify sensitizing <italic>EGFR </italic>mutations of non-small cell lung cancer (NSCLC) patients. Nevertheless, the detection and treatment response of NSCLC patients with concurrent L858R and uncommon <italic>EGFR<...

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Literature Corpus work: 74c7b767-a566-5a1c-9bb2-504bf2fdebb0
DOI: 10.21203/rs.3.rs-5234168/v1

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