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Rapid Detection and Inhibition of SARS-CoV-2-Spike Mutation-Mediated Microthrombosis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) - 1 Dec 2021

Satta Sandro, Lai Angela, Cavallero Susana, Williamson Cayden, Chen Justin, Blázquez-Medela Ana M, Roustaei Mehrdad, Dillon Barbara J, Ashammakhi Nureddin, Carlo Dino Di, Li Zhaoping, Sun Ren, Hsiai Tzung K

Abstract excerpt

Activation of endothelial cells following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is thought to be the primary driver for the increasingly recognized thrombotic complications in coronavirus disease 2019 patients, potentially due to the SARS-CoV-2 Spike protein binding to the human angiotensin-converting enzyme 2 (hACE2). Vaccination therapies use the same Spike sequence or protein...

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Identifiers

PMID: 34687279
DOI: 10.1002/advs.202103266
PMCID: PMC8646611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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