Article
Blood-Based Immune Profiling Combined with Machine Learning Discriminates Psoriatic Arthritis from Psoriasis Patients.
International journal of molecular sciences - 12 Oct 2021
Mulder Michelle L M, He Xuehui, van den Reek Juul M P A, Urbano Paulo C M, Kaffa Charlotte, Wang Xinhui, van Cranenbroek Bram, van Rijssen Esther, van den Hoogen Frank H J, Joosten Irma, Alkema Wynand, de Jong Elke M G J, Smeets Ruben L, Wenink Mark H, Koenen Hans J P M
Abstract excerpt
Psoriasis (Pso) is a chronic inflammatory skin disease, and up to 30% of Pso patients develop psoriatic arthritis (PsA), which can lead to irreversible joint damage. Early detection of PsA in Pso patients is crucial for timely treatment but difficult for dermatologists to implement. We, therefore, aimed to find disease-specific immune profiles, discriminating Pso from PsA patients, possibly facilitating the...
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