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Article

Association of PIP4K2A Polymorphisms with Alcohol Use Disorder.

Genes - 19 Oct 2021

Fedorenko Olga Yu, Mikhalitskaya Ekaterina V, Toshchakova Valentina A, Loonen Anton J M, Bokhan Nikolay A, Ivanova Svetlana A

Abstract excerpt

BACKGROUND: Alcohol use disorder (AUD) not only influences individuals and families but also has a lasting social impact on communities at the national level. Dopaminergic neurotransmission is involved in excessive alcohol consumption. Phosphatidylinositol-5-phosphate-4-kinase type 2 α (PIP4K2A) plays an important role in the regulation of ascending dopamine pathways. In this study; we determined possible...

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Identifiers

PMID: 34681036
DOI: 10.3390/genes12101642
PMCID: PMC8535504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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