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Nicotinamide N-Methyltransferase: An Emerging Protagonist in Cancer Macro(r)evolution

28 Sept 2021

Abstract excerpt

-methyltransferase (NNMT) has progressed from being considered merely a Phase II metabolic enzyme to one with a central role in cell function and energy metabolism. Over the last three decades, a significant body of evidence has accumulated which clearly demonstrates a central role for NNMT in cancer survival, metastasis, and drug resistance. In this review, we discuss the evidence supporting a role for NNMT in...

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PMID: 34680055
DOI: 10.3390/biom11101418

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