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Nicotinamide N-Methyltransferase: A Promising Biomarker and Target for Human Cancer Therapy

9 Jun 2022

Abstract excerpt

Cancer cells typically exhibit a tightly regulated program of metabolic plasticity and epigenetic remodeling to meet the demand of uncontrolled cell proliferation. The metabolic–epigenetic axis has recently become an increasingly hot topic in carcinogenesis and offers new avenues for innovative and personalized cancer treatment strategies. NicotinamideN-methyltransferase (NNMT) is a metabolic enzyme involved in...

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PMID: 35756670
DOI: 10.3389/fonc.2022.894744

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