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Article

Genetic variants predictive of chemotherapy-induced peripheral neuropathy symptoms in gynecologic cancer survivors.

Gynecologic oncology - 1 Dec 2021

Thomaier Lauren, Darst Burcu F, Jewett Patricia, Hoffmann Cody, Brown Katherine, Makaram Aditi, Blaes Anne, Argenta Peter, Teoh Deanna, Vogel Rachel I

Abstract excerpt

OBJECTIVE: To identify genetic variants associated with chemotherapy-induced peripheral neuropathy (CIPN) symptoms among gynecologic cancer survivors and determine the variants' predictive power in addition to age and clinical factors at time of diagnosis. METHODS: Participants of a prospective cohort study on gynecologic cancers provided a DNA saliva sample and reported CIPN symptoms (FACT/GOG-Ntx). Genotyping...

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Identifiers

PMID: 34674889
DOI: 10.1016/j.ygyno.2021.10.006
PMCID: PMC9310052

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