Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long non-coding RNA MEG3 promotes cisplatin-induced nephrotoxicity through regulating AKT/TSC/mTOR-mediated autophagy

1 Jan 2021

Abstract excerpt

Cis-Diamminedichloroplatinum (II) (DDP)-induced nephrotoxicity (DDPIN) may cause irreversible renal injury associated with high morbidity and mortality. Current standard therapies have not achieved satisfactory clinical outcomes due to unclear molecular and cellular mechanisms. Therefore, exploring potential therapies on DDPIN represents an urgent medical need. Present study characterized the role of lncRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Organ Transplantation Techniques and Outcomes
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34671212
DOI: 10.7150/ijbs.58910

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long non-coding RNA MEG3 promotes cisplatin-induced nephrotoxicity through regulating AKT/TSC/mTOR-mediated autophagyPMID 34671212Read ↗

A Comprehensive Review on the Genetic Regulation of Cisplatin-induced NephrotoxicitySemantic proximity Read ↗

Epigenetic Mechanisms Involved in Cisplatin-Induced Nephrotoxicity: An UpdateSemantic proximity Read ↗

Can Cisplatin Therapy Be Improved? Pathways That Can Be TargetedSemantic proximity Read ↗

MicroRNA-mediated attenuation of branched-chain amino acid catabolism promotes ferroptosis in chronic kidney diseaseSemantic proximity Read ↗

Circular RNA expression profiles in cisplatin-induced acute kidney injury in miceSemantic proximity Read ↗

Long Noncoding RNAs as Biotargets in Cisplatin-Based Drug ResistanceSemantic proximity Read ↗

Genome-Wide Analyses of Nephrotoxicity in Platinum-Treated Cancer Patients Identify Association with Genetic Variant in RBMS3 and Acute Kidney InjurySemantic proximity Read ↗

PRMT4 interacts with NCOA4 to inhibit ferritinophagy in cisplatin-induced acute kidney injurySemantic proximity Read ↗

Long non-coding RNA MEG3 promotes fibrosis and inflammatory response in diabetic nephropathy via miR-181a/Egr-1/TLR4 axisSemantic proximity Read ↗

The circadian clock gene Bmal1 facilitates cisplatin-induced renal injury and hepatizationSemantic proximity Read ↗

The IDH1-R132H mutation aggravates cisplatin-induced acute kidney injury by promoting ferroptosis through disrupting NDUFA1 and FSP1 interactionSemantic proximity Read ↗

Epigenetic Regulation in Kidney Toxicity: Insights From Cisplatin NephrotoxicitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.