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Article

LAMP2A regulates cisplatin resistance in colorectal cancer through mediating autophagy

8 May 2024

Abstract excerpt

BACKGROUND: Drug resistance is an important constraint on clinical outcomes in advanced cancers. LAMP2A is a limiting protein in molecular chaperone-mediated autophagy. This study was aimed to explore LAMP2A function in cisplatin (cis-diamminedichloroplatinum, DDP) resistance colorectal cancer (CRC) to seek new ideas for CRC clinical treatment. METHODS: In this study, LAMP2A expression was analyzed by molecular...

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PMID: 38717639
DOI: 10.1007/s00432-024-05775-6

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