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Article

Differences in Prostate Cancer Genomes by Self-reported Race: Contributions of Genetic Ancestry, Modifiable Cancer Risk Factors, and Clinical Factors

19 Oct 2021

Abstract excerpt

Abstract Purpose: Black men die from prostate cancer twice as often as White men, a disparity likely due to inherited genetics, modifiable cancer risk factors, and healthcare access. It is incompletely understood how and why tumor genomes differ by self-reported race and genetic ancestry. Experimental Design: Among 2,069 men with prostate cancer (1,841 self-reported White, 63 Asian, 165 Black) with access to...

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PMID: 34667026
DOI: 10.1158/1078-0432.ccr-21-2577

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