Article
Two regulatory factors of Vibrio cholerae activating the mannose-sensitive haemagglutinin pilus expression is important for biofilm formation and colonization in mice.
Microbiology (Reading, England) - 1 Oct 2021
Shi Mengting, Zheng Yue, Wang Xianghong, Wang Zhengjia, Yang Menghua
Abstract excerpt
Vibrio cholerae the causative agent of cholera, uses a large number of coordinated transcriptional regulatory events to transition from its environmental reservoir to the host intestine, which is its preferred colonization site. Transcription of the mannose-sensitive haemagglutinin pilus (MSHA), which aids the persistence of V. cholerae in aquatic environments, but causes its clearance by host immune defenses,...
Topics
- Animals
- Bacterial Proteins
- Biofilms
- Cell Membrane
- Cholera
- Fimbriae Proteins
- Gene Expression Regulation, Bacterial
- Mannose-Binding Lectin
- Mice
- Mutation
- Operon
- Promoter Regions, Genetic
- Vibrio cholerae
- Virulence