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Article

Rediscover: an R package to identify mutually exclusive mutations.

Bioinformatics (Oxford, England) - 12 Jan 2022

Ferrer-Bonsoms Juan A, Jareno Laura, Rubio Angel

Abstract excerpt

MOTIVATION: Discover is an algorithm developed to identify mutually exclusive genomic events. Its main contribution is a statistical analysis based on the Poisson-Binomial (PB) distribution to take into account the mutation rate of genes and samples. Discover is very effective for identifying mutually exclusive mutations at the expense of speed in large datasets: the PB is computationally costly to estimate, and...

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PMID: 34664620
DOI: 10.1093/bioinformatics/btab709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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