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Article

Development of the variant calling algorithm, ADIScan, and its use to estimate discordant sequences between monozygotic twins.

Nucleic acids research - 6 Sept 2018

Cho Yangrae, Lee Sunho, Hong Jong Hui, Kim Byong Joon, Hong Woon-Young, Jung Jongcheol, Lee Hyang Burm, Sung Joohon, Kim Han-Na, Kim Hyung-Lae, Jung Jongsun

Abstract excerpt

Calling variants from next-generation sequencing (NGS) data or discovering discordant sequences between two NGS data sets is challenging. We developed a computer algorithm, ADIScan1, to call variants by comparing the fractions of allelic reads in a tester to the universal reference genome. We then created ADIScan2 by modifying the algorithm to directly compare two sets of NGS data and predict discordant sequences...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29873758
DOI: 10.1093/nar/gky445
PMCID: PMC6125643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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