Back to search

Article

All <sup>2</sup> : A tool for selecting mosaic mutations from comprehensive multi-cell comparisons

2021-09-30

Abstract excerpt

Accurate discovery of somatic mutations in a cell is a challenge that partially lays in immaturity of dedicated analytical approaches. Approaches comparing cell’s genome to a control bulk sample miss common mutations, while approaches to find such mutations from bulk suffer from low sensitivity. We developed a tool, All 2 , which enables accurate filtering of mutations in a cell from exhaustive comparison of cell...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b3a69077-761e-550f-a80a-f16e303abbb2
DOI
10.1101/2021.09.29.462281
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
All <sup>2</sup> : A tool for selecting mosaic mutations from comprehensive multi-cell comparisonsDOI 10.1101/2021.09.29.462281
Select a neighboring publication to make it the new centre.