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LncRNA MALAT1 was regulated by HPV16 E7 independently of pRB in cervical cancer cells

1 Jan 2021

Abstract excerpt

High-risk human papillomavirus (HPV) infection was one of the first step in the process of carcinogenesis in cervical cancers. The expression of viral oncoprotein E7 was essential in this process by inactivating the tumor suppressor proteins RB, in addition to interacting with other host proteins. LncRNA MALAT1 was found to be altered in human cervical cancer tissues, suggesting an important role in...

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PMID: 34659524
DOI: 10.7150/jca.61194

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