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Article

Influence of PICALM and CLU risk variants on beta EEG activity in Alzheimer's disease patients.

Scientific reports - 14 Oct 2021

Maturana-Candelas Aarón, Gómez Carlos, Poza Jesús, Rodríguez-González Víctor, Pablo Vìctor Gutiérrez-de, Lopes Alexandra M, Pinto Nadia, Hornero Roberto

Abstract excerpt

PICALM and CLU genes have been linked to alterations in brain biochemical processes that may have an impact on Alzheimer's disease (AD) development and neurophysiological dynamics. The aim of this study is to analyze the relationship between the electroencephalographic (EEG) activity and the PICALM and CLU alleles described as conferring risk or protective effects on AD patients and healthy controls. For this...

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Identifiers

PMID: 34650147
DOI: 10.1038/s41598-021-99589-y
PMCID: PMC8516883

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