Article
Quantitative EEG during normal aging: association with the Alzheimer's disease genetic risk variant in PICALM gene.
Neurobiology of aging - 1 Mar 2017
Ponomareva Natalya V, Andreeva Tatiana V, Protasova Maria S, Shagam Lef I, Malina Daria D, Goltsov Andrey Yu, Fokin Vitaly F, Illarioshkin Sergey N, Rogaev Evgeny I
Abstract excerpt
Genome-wide association studies have identified novel risk variants for Alzheimer's disease (AD). Among these, a gene carrying one of the highest risks for AD is PICALM. The PICALM rs3851179 A allele is thought to have a protective effect, whereas the G allele appears to confer risk for AD. The influence of the PICALM genotype on brain function in nondemented subjects remains largely unknown. We examined the...
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