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Genetic Association Between Alzheimer’s Disease Risk Variant of the PICALM Gene and EEG Functional Connectivity in Non-demented Adults

16 Apr 2020

Abstract excerpt

Genome wide association studies (GWAS) have identified and validated the association of the PICALM genotype with Alzheimer’s disease (AD). The PICALM rs3851179 A allele is thought to have a protective effect, whereas the G allele appears to confer risk for AD. The influence of the PICALM genotype on brain functional connectivity in non-demented subjects remains largely unknown. We examined the association of the...

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PMID: 32372909
DOI: 10.3389/fnins.2020.00324

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