Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Therapeutically leveraging GABA A receptors in cancer

1 Oct 2021

Abstract excerpt

γ-aminobutyric acid or GABA is an amino acid that functionally acts as a neurotransmitter and is critical to neurotransmission. GABA is also a metabolite in the Krebs cycle. It is therefore unsurprising that GABA and its receptors are also present outside of the central nervous system, including in immune cells. This observation suggests that GABAergic signaling impacts events beyond brain function and possibly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Stress, Anesthesia, and Immune Response
Share to Neuroscience and Neuropharmacology Research
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34649481
DOI: 10.1177/15353702211032549

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Therapeutically leveraging GABA A receptors in cancerPMID 34649481Read ↗

The Emerging Roles of π Subunit-Containing GABAA Receptors in Different CancersSemantic proximity Read ↗

Expression of gamma-aminobutyric acid receptors on neoplastic growth and prediction of prognosis in non-small cell lung cancer.Semantic proximity Read ↗

Distinct diagnostic and prognostic values of γ‑aminobutyric acid type A receptor family genes in patients with colon adenocarcinomaSemantic proximity Read ↗

The GABAA receptor family: molecular and functional diversity.Semantic proximity Read ↗

Interplay between microbial‐derived GABA and host GABA receptor signaling collectively influence the tumorigenic function of GABA in colon cancerSemantic proximity Read ↗

Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes.Semantic proximity Read ↗

The GABAA receptors. From subunits to diverse functions.Semantic proximity Read ↗

Investigation into the Association between Neurotransmitters, Immune Features, and Lung Adenocarcinoma: A Multi-Omics Approach to the Identification of GABA-Related Features Employing 101 Combinatorial Machine Learning Computational FrameworksSemantic proximity Read ↗

Altered GABAergic Signaling in Brain Disease at Various Stages of LifeSemantic proximity Read ↗

GABRB2, a key player in neuropsychiatric disorders and beyond.Semantic proximity Read ↗

From ion currents to genomic analysis: recent advances in GABAA receptor research.Semantic proximity Read ↗

GABAergic signaling contributes to tumor cell invasion and poor overall survival in colorectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.