Article
Deep sequencing of hepatitis B virus using Ion Torrent fusion primer method.
Journal of virological methods - 1 Jan 2022
Ringlander Johan, Andersson Maria E, Prakash Kasthuri, Larsson Simon B, Lindh Magnus
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) infection is worldwide a major cause of liver cirrhosis and hepatocellular carcinoma. Thousands of years ago, several HBV genotypes (A-I) evolved and have, as a result of human migration, become globally disseminated. Sequencing of HBV is used for genotyping, and investigation of outbreaks or of antiviral resistance. The present study describes a simplified deep sequencing of...
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