Endoscopic liquid biopsies of gastric fluid in a large patient cohort reveal DNA content as a candidate tumor biomarker in gastric cancer

Abstract excerpt

<h4>Background</h4> Human gastric cancer remains a diagnostic and therapeutic challenge worldwide. Improved prognostic biomarkers may support treatment planning, including surgery, neoadjuvant and adjuvant therapies. We offer a new liquid biopsy approach, integrated with esophagogastroduodenoscopy (EGD) to evaluate gastric fluid recovered from a large patient cohort (n=1,056 patients), demonstrating the value of...

Topics

Open a Topic to create a Post that cites this publication.

• Antigens, Tumor-Associated, Carbohydrate
• Cancer Genomics and Diagnostics
• Cell-Free Nucleic Acids
• Enzyme-Linked Immunosorbent Assay
• Exome Sequencing
• Liquid Biopsy
• Machine Learning
• Stomach Neoplasms

Identifiers and source

Literature Corpus work

357a4b5e-5ea4-50c0-b4c9-3d3bcf1671e9

DOI

10.1101/2023.02.14.23285919