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Mitophagy Regulates Neurodegenerative Diseases

24 Jul 2021

Abstract excerpt

Mitochondria play an essential role in supplying energy for the health and survival of neurons. Mitophagy is a metabolic process that removes dysfunctional or redundant mitochondria. This process preserves mitochondrial health. However, defective mitophagy triggers the accumulation of damaged mitochondria, causing major neurodegenerative disorders. This review introduces molecular mechanisms and signaling...

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PMID: 34440645
DOI: 10.3390/cells10081876

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