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Development of a competitive ELISA for detecting antibodies against genotype 1 hepatitis E virus.

Applied microbiology and biotechnology - 1 Nov 2021

Zhang Beibei, Fan Jie, Luo Yuhang, Lv Huanhuan, Zhao Qin, Fan Mengnan, Duan Hong, Liu Baoyuan, Nan Yuchen, Sun Yani, Zhou En-Min

Abstract excerpt

Hepatitis E, a significant global public health issue in China, is caused by sporadic infections with regional hepatitis E virus (HEV) genotypes 1, 3, and 4. To date, most immunoassays currently used to test human sera for the presence of anti-HEV antibodies cannot identify HEV at the genotype level. However, such information would be useful for identifying the source of infecting virus. Therefore, here we...

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PMID: 34633486
DOI: 10.1007/s00253-021-11621-3

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