Article
Restricted enzooticity of hepatitis E virus genotypes 1 to 4 in the United States.
Journal of clinical microbiology - 1 Dec 2011
Dong Chen, Meng Jihong, Dai Xing, Liang Jiu-Hong, Feagins Alicia R, Meng Xiang-Jin, Belfiore Natalia M, Bradford Carol, Corn Joseph L, Cray Carolyn, Glass Gregory E, Gordon Melvin L, Hesse Richard A, Montgomery Donald L, Nicholson William L, Pilny Anthony A, Ramamoorthy Sheela, Shaver Douglas D, Drobeniuc Jan, Purdy Michael A, Fields Howard A, Kamili Saleem, Teo Chong-Gee
Abstract excerpt
Hepatitis E is recognized as a zoonosis, and swine are known reservoirs, but how broadly enzootic its causative agent, hepatitis E virus (HEV), is remains controversial. To determine the prevalence of HEV infection in animals, a serological assay with capability to detect anti-HEV-antibody across a wide variety of animal species was devised. Recombinant antigens comprising truncated capsid proteins generated from...
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