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Article

Development and validation of a genotype 3 recombinant protein-based immunoassay for hepatitis E virus serology in swine.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Apr 2014

van der Poel W H M, Pavio N, van der Goot J, van Es M, Martin M, Engel B

Abstract excerpt

Hepatitis E virus (HEV) is classified within the family Hepeviridae, genus Hepevirus. HEV genotype 3 (Gt3) infections are endemic in pigs in Western Europe and in North and South America and cause zoonotic infections in humans. Several serological assays to detect HEV antibodies in pigs have been developed, at first mainly based on HEV genotype 1 (Gt1) antigens. To develop a sensitive HEV Gt3 ELISA, a recombinant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24676472
DOI: 10.1590/1414-431x20133249
PMCID: PMC4075298

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