Article
Subventricular zone involvement is associated with worse outcome in glioma WHO grade 2 depending on molecular markers.
Scientific reports - 8 Oct 2021
Karschnia Philipp, Weller Jonathan, Blobner Jens, Stoecklein Veit M, Dorostkar Mario M, Rejeski Kai, Forbrig Robert, Niyazi Maximilian, von Baumgarten Louisa, Dietrich Jorg, Tonn Joerg-Christian, Thon Niklas
Abstract excerpt
Neural stem cells within the subventricular zone were identified as cells of origin driving growth of high-grade gliomas, and anatomical involvement of the subventricular zone has been associated with an inferior clinical outcome. Whether the association between poor outcome and subventricular zone involvement also applies to glioma of lower grades is unclear. We therefore analysed a retrospective cohort of 182...
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