Article
Changes in B Cell Pool of Patients With Multibacillary Leprosy: Diminished Memory B Cell and Enhanced Mature B in Peripheral Blood.
Frontiers in immunology - 1 Jan 2021
Nogueira Otto Castro, Gandini Mariana, Cabral Natasha, de Figueiredo Vilma, Rodrigues-da-Silva Rodrigo Nunes, Lima-Junior Josué da Costa, Pinheiro Roberta Olmo, Pereira Geraldo Moura Batista, Pessolani Maria Cristina Vidal, de Macedo Cristiana Santos
Abstract excerpt
Despite being treatable, leprosy still represents a major public health problem, and many mechanisms that drive leprosy immunopathogenesis still need to be elucidated. B cells play important roles in immune defense, being classified in different subgroups that present distinct roles in the immune response. Here, the profile of B cell subpopulations in peripheral blood of patients with paucibacillary (TT/BT),...
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