Mutant KRAS as a prognostic biomarker after hepatectomy for rectal cancer metastases: Does the primary disease site matter?

doi:10.1002/jhbp.1054

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Article

Mutant KRAS as a prognostic biomarker after hepatectomy for rectal cancer metastases: Does the primary disease site matter?

Journal of hepato-biliary-pancreatic sciences - 1 Apr 2022

Amini Neda, Andreatos Nikolaos, Margonis Georgios Antonios, Buettner Stefan, Wang Jaeyun, Galjart Boris, Wagner Doris, Sasaki Kazunari, Angelou Anastasios, Sun Jinger, Kamphues Carsten, Beer Andrea, Morioka Daisuke, Løes Inger Marie, Antoniou Efstathios, Imai Katsunori, Pikoulis Emmanouil, He Jin, Kaczirek Klaus, Poultsides George, Verhoef Cornelis, Lønning Per Eystein, Endo Itaru, Baba Hideo, Kornprat Peter, NAucejo Federico, Kreis Martin E, Christopher Wolfgang L, Weiss Matthew J, Safar Bashar, Burkhart Richard Andrew

Abstract excerpt

BACKGROUND: The prognostic implication of mutant KRAS (mKRAS) among patients with primary disease in the rectum remains unknown. METHODS: From 2000 to 2018, patients undergoing hepatectomy for colorectal liver metastases at 10 collaborating international institutions with documented KRAS status were surveyed. RESULTS: A total of 834 (65.8%) patients with primary colon cancer and 434 (34.2%) patients with primary...

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PMID: 34614304
DOI: 10.1002/jhbp.1054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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