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Bacteria of the order Burkholderiales are original environmental hosts of type II trimethoprim resistance genes (dfrB)

1 Jan 2024

Abstract excerpt

It is consensus that clinically relevant antibiotic resistance genes have their origin in environmental bacteria, including the large pool of primarily benign species. Yet, for the vast majority of acquired antibiotic resistance genes, the original environmental host(s) has not been identified to date. Closing this knowledge gap could improve our understanding of how antimicrobial resistance proliferates in the...

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PMID: 39658215
DOI: 10.1093/ismejo/wrae243

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