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Article

Outcomes After Breast Radiation Therapy in a Diverse Patient Cohort With a Germline BRCA1/2 Mutation.

International journal of radiation oncology, biology, physics - 1 Feb 2022

Chapman Bhavana V, Liu Diane, Shen Yu, Olamigoke Oluwafikayo O, Lakomy David S, Barrera Angelica M Gutierrez, Stecklein Shane R, Sawakuchi Gabriel O, Bright Scott J, Bedrosian Isabelle, Litton Jennifer K, Smith Benjamin D, Woodward Wendy A, Perkins George H, Hoffman Karen E, Stauder Michael C, Strom Eric A, Arun Banu K, Shaitelman Simona F

Abstract excerpt

PURPOSE: BRCA1/2 pathogenic variant (PV) mutations confer radiation sensitivity preclinically, but there are limited data regarding breast cancer outcomes after radiation therapy (RT) among patients with documented BRCA1/2 PV mutations versus no PV mutations. METHODS AND MATERIALS: This retrospective cohort study included women with clinical stage I-III breast cancer who received definitive surgery and RT and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 34610390
DOI: 10.1016/j.ijrobp.2021.09.033
PMCID: PMC9330175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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