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Article

Breast Radiation Therapy-Related Treatment Outcomes in Patients With or Without Germline Mutations on Multigene Panel Testing.

International journal of radiation oncology, biology, physics - 1 Feb 2022

Chapman Bhavana V, Liu Diane, Shen Yu, Olamigoke Oluwafikayo O, Lakomy David S, Barrera Angelica M Gutierrez, Stecklein Shane R, Sawakuchi Gabriel O, Bright Scott J, Bedrosian Isabelle, Litton Jennifer K, Smith Benjamin D, Woodward Wendy A, Perkins George H, Hoffman Karen E, Stauder Michael C, Strom Eric A, Arun Banu K, Shaitelman Simona F

Abstract excerpt

PURPOSE: Multigene panel testing has increased the detection of germline mutations in patients with breast cancer. The implications of using radiation therapy (RT) to treat patients with pathogenic variant (PV) mutations are not well understood and have been studied mostly in women with only BRCA1 or BRCA2 PVs. We analyzed oncologic outcomes and toxicity after adjuvant RT in a contemporary, diverse cohort of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34582940
DOI: 10.1016/j.ijrobp.2021.09.026
PMCID: PMC8748284

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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