Article
New structural variation in evolutionary searches of RNA neutral networks.
Bio Systems - 1 Jan 2000
Sumedha, Martin Olivier C, Wagner Andreas
Abstract excerpt
RNA secondary structure is an important computational model to understand how genetic variation maps into phenotypic (structural) variation. Evolutionary innovation in RNA structures is facilitated by neutral networks, large connected sets of RNA sequences that fold into the same structure. Our work extends and deepens previous studies on neutral networks. First, we show that even the 1-mutant neighborhood of a...
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