Article
Intravascular Crawling of Patrolling Monocytes: A Lèvy-Like Motility for Unique Search Functions?
Frontiers in immunology - 1 Jan 2021
Moreno-Cañadas Rocío, Luque-Martín Laura, Arroyo Alicia G
Abstract excerpt
Patrolling monocytes (PMo) are the organism's preeminent intravascular guardians by their continuous search of damaged endothelial cells and harmful microparticles for their removal and to restore homeostasis. This surveillance is accomplished by PMo crawling on the apical side of the endothelium through regulated interactions of integrins and chemokine receptors with their endothelial ligands. We propose that...
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