Article
Scavenger Receptor CD36 Directs Nonclassical Monocyte Patrolling Along the Endothelium During Early Atherogenesis.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2017
Marcovecchio Paola M, Thomas Graham D, Mikulski Zbigniew, Ehinger Erik, Mueller Karin A L, Blatchley Amy, Wu Runpei, Miller Yury I, Nguyen Anh Tram, Taylor Angela M, McNamara Coleen A, Ley Klaus, Hedrick Catherine C
Abstract excerpt
OBJECTIVE: Nonclassical monocytes (NCM) function to maintain vascular homeostasis by crawling or patrolling along the vessel wall. This subset of monocytes responds to viruses, tumor cells, and other pathogens to aid in protection of the host. In this study, we wished to determine how early atherogenesis impacts NCM patrolling in the vasculature. APPROACH AND RESULTS: To study the role of NCM in early...
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