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Applications of single-cell genomics and computational strategies to study common disease and population-level variation.

Genome research - 1 Oct 2021

Auerbach Benjamin J, Hu Jian, Reilly Muredach P, Li Mingyao

Abstract excerpt

The advent and rapid development of single-cell technologies have made it possible to study cellular heterogeneity at an unprecedented resolution and scale. Cellular heterogeneity underlies phenotypic differences among individuals, and studying cellular heterogeneity is an important step toward our understanding of the disease molecular mechanism. Single-cell technologies offer opportunities to characterize...

Topics

Genome-Wide Association Study
Genomics
Phenotype
Single-Cell Analysis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34599006
DOI: 10.1101/gr.275430.121
PMCID: PMC8494214

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