Article
A novel regQTL-SNP and the risk of lung cancer: a multi-dimensional study.
Archives of toxicology - 1 Dec 2021
Yu Yuhui, Mao Liping, Cheng Zhounan, Zhu Xiaoqi, Cui Jiahua, Fu Xiaoyu, Cheng Jingwen, Zhou Yan, Qiu Anni, Dong Yang, Zhuang Xun, Lu Yihua, Lian Yulong, Tian Tian, Wu Shuangshuang, Chu Minjie
Abstract excerpt
RegQTL, a novel concept, indicates that different genotypes of some SNPs have differential effects on the expression patterns of miRNAs and their target mRNAs. We aimed to identify the association between regQTL-SNPs and lung cancer risk and to explore the underlying mechanisms. The two-stage case-control study included the first stage in a Chinese population (626 lung cancer cases and 667 healthy controls) and...
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