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NLRP3 gene polymorphisms and expression in rheumatoid arthritis

3 Aug 2021

Abstract excerpt

The present study aimed to investigate the association between the single-nucleotide polymorphisms (SNPs) rs4612666 and rs10754558 in the NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) gene and the susceptibility to rheumatoid arthritis (RA) in a Han Chinese population. mRNA expression of NLRP3, apoptosis-associated speck-like protein (ASC), and caspase-1 were determined in peripheral blood mononuclear...

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Identifiers

PMID: 34504564
DOI: 10.3892/etm.2021.10544

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