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Article

BAP1 methylation: a prognostic marker of uveal melanoma metastasis

30 Sept 2021

Abstract excerpt

Uveal melanoma, the most common intraocular primary cancer in adults, is characterized by striking variability in metastatic tendencies. BAP1 deletion in the primary tumor is associated with uveal melanoma metastasis, but it cannot always be resolved by bulk DNA sequencing of heterogeneous tumors. Here, we show that assessment of BAP1 methylation is an accurate and readily clinically actionable assay to...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 34593944
DOI: 10.1038/s41698-021-00226-8

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