Article
MuWU: Mutant-seq library analysis and annotation.
Bioinformatics (Oxford, England) - 12 Jan 2022
Stöcker Tyll, Altrogge Lena, Marcon Caroline, Win Yan Naing, Hochholdinger Frank, Schoof Heiko
Abstract excerpt
MOTIVATION: Insertional mutagenesis allows for the creation of loss-of-function mutations on a genome-wide scale. In theory, every gene can be 'knocked out' via the insertion of an additional DNA sequence. Resources of sequence-indexed mutants of plant and animal model organisms are instrumental for functional genomics studies. Such repositories significantly speed up the acquisition of interesting genotypes and...
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