MuWU: Mutant-seq library analysis and annotation.

doi:10.1093/bioinformatics/btab679

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Article

MuWU: Mutant-seq library analysis and annotation.

Bioinformatics (Oxford, England) - 12 Jan 2022

Stöcker Tyll, Altrogge Lena, Marcon Caroline, Win Yan Naing, Hochholdinger Frank, Schoof Heiko

Abstract excerpt

MOTIVATION: Insertional mutagenesis allows for the creation of loss-of-function mutations on a genome-wide scale. In theory, every gene can be 'knocked out' via the insertion of an additional DNA sequence. Resources of sequence-indexed mutants of plant and animal model organisms are instrumental for functional genomics studies. Such repositories significantly speed up the acquisition of interesting genotypes and...

Topics

Animals
Mutagenesis, Insertional
DNA Transposable Elements
Genomics
Mutation
Gene Library
Zea mays

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Identifiers

PMID: 34586393
DOI: 10.1093/bioinformatics/btab679
PMCID: PMC8756183

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