Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Podofilox suppresses gastric cancer cell proliferation by regulating cell cycle arrest and the c‑Myc/ATG10 axis

23 Aug 2021

Abstract excerpt

Gastric cancer (GC) is a malignancy for which effective therapeutic drugs are limited. Podofilox exhibits antitumor effects in various types of cancer; however, whether it may inhibit GC growth remains unknown. The aim of the present study was to investigate the role of podofilox in GC. Cell Counting Kit‑8, colony formation and cell cycle assays were used to detect the role of podofilox on cellular proliferation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer Mechanisms and Therapy
Share to PI3K/AKT/mTOR signaling in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34584548
DOI: 10.3892/etm.2021.10637

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Podofilox suppresses gastric cancer cell proliferation by regulating cell cycle arrest and the c‑Myc/ATG10 axisPMID 34584548Read ↗

GPX4 Regulates Tumor Cell ProliferationviaSuppressing Ferroptosis and Exhibits Prognostic Significance in Gastric CancerSemantic proximity Read ↗

PTBP1 knockdown impairs autophagy flux and inhibits gastric cancer progression through TXNIP-mediated oxidative stressSemantic proximity Read ↗

FOXO3a‐dependent Parkin regulates the development of gastric cancer by targeting ATP‐binding cassette transporter E1Semantic proximity Read ↗

GPX4 predicts poor prognosis and regulates tumor proliferation and senescence in colorectal adenocarcinomaSemantic proximity Read ↗

Cisplatin promotes pyroptosis of gastric cancer cells by activating GSDMESemantic proximity Read ↗

α-Tomatine Inhibits Proliferation, Metastasis, Drug Resistance and Immune Infiltration Through the PI3K-AKT-MAPK Axis in Gastric CancerSemantic proximity Read ↗

G protein pathway suppressor 2 suppresses gastric cancer by destabilizing epidermal growth factor receptorSemantic proximity Read ↗

CircSCUBE3 Reduces the Anti-gastric Cancer Activity of Anti-PD-L1Semantic proximity Read ↗

Celastrol inhibits gastric cancer cell proliferation, migration, and invasion via the FOXA1/CLDN4 axisSemantic proximity Read ↗

CPX Targeting DJ-1 Triggers ROS-induced Cell Death and Protective Autophagy in Colorectal CancerSemantic proximity Read ↗

Cucurbitacin B induces autophagy and apoptosis by suppressing CIP2A/PP2A/mTORC1 signaling axis in human cisplatin resistant gastric cancer cellsSemantic proximity Read ↗

Growth arrest‐specific gene 1 is downregulated and inhibits tumor growth in gastric cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.