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Article

GPX4 predicts poor prognosis and regulates tumor proliferation and senescence in colorectal adenocarcinoma

1 Jan 2025

Abstract excerpt

Background: Colorectal adenocarcinoma (COAD) is one of the most common gastrointestinal malignancies. There is a pressing need to recognize reliable biomarkers that can improve diagnostic accuracy, predict prognosis, and serve as effective molecular targets. Glutathione peroxidase 4 (GPX4) is an important antioxidant protein. Evidence demonstrates that abnormal expression of GPX4 is related to cancer initiation...

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PMID: 40746894
DOI: 10.32604/or.2025.063395

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