Article
Defective Efferocytosis in a Murine Model of Sjögren's Syndrome Is Mediated by Dysfunctional Mer Tyrosine Kinase Receptor.
International journal of molecular sciences - 8 Sept 2021
Witas Richard, Rasmussen Astrid, Scofield Robert H, Radfar Lida, Stone Donald U, Grundahl Kiely, Lewis David, Sivils Kathy L, Lessard Christopher J, Farris A Darise, Nguyen Cuong Q
Abstract excerpt
Sjögren's syndrome (SjS) is a chronic autoimmune disease primarily involving the exocrine glands in which the involvement of the innate immune system is largely uncharacterized. Mer signaling has been found to be protective in several autoimmune diseases but remains unstudied in SjS. Here, we investigated the role of Mer signaling in SjS. Mer knockout (MerKO) mice were examined for SjS disease criteria....
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